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Drug ReportsFlutemetamol (18f)
Flutemetamol f 18
Vizamyl (flutemetamol f 18) is a small molecule pharmaceutical. Flutemetamol f 18 was first approved as Vizamyl on 2013-10-25. It has been approved in Europe to treat alzheimer disease and radionuclide imaging.
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Therapeutic Areas
Therapeutic Area
MeSH
nervous system diseasesD009422
diagnosisD003933
mental disordersD001523
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Last Update
vizamylNew Drug Application2023-04-03
Indications
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FDA Information
Flutemetamol F-18, Vizamyl, Ge Healthcare
89161312028-09-16DP
72708002025-09-03DS, DPU-336
82362822024-05-21DS, DP
73514012023-01-24DS, DPU-336
86911852023-01-24U-336
ATC Codes
V: Various drug classes in atc
V09: Diagnostic radiopharmaceuticals
V09A: Central nervous system diagnostic radiopharmaceuticals
V09AX: Other central nervous system diagnostic radiopharmaceuticals in atc
V09AX04: Flutemetamol (18f)
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Drug
General
Drug common nameFlutemetamol f 18
INNflutemetamol (18f)
Description
Flutemetamol ((18)F) is a member of the class of benzothiazoles that is 1,3-benzothiazole substituted by 3-((18)F)fluoro-4-(methylamino)phenyl and hydroxy groups at positions 3 and 6 respectively. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease. It has a role as a radioactive imaging agent. It is a (18)F radiopharmaceutical, a member of benzothiazoles, an aromatic amine and a secondary amino compound.
Classification
Small molecule
Drug class
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Structure (InChI/SMILES or Protein Sequence)
CNc1ccc(-c2nc3ccc(O)cc3s2)cc1[18F]
Identifiers
PDB
CAS-ID765922-62-1
RxCUI
ChEMBL IDCHEMBL2042122
ChEBI ID76611
PubChem CID15950376
DrugBank
UNII IDL49M066S0O (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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